ESPE Abstracts

Introduction: The hypothalamo-pituitary system is activated as puberty begins and GnRH release occurs as well as the synthesis of many hormones. These hormones cause changes on muscle development, body fat distribution. In this study, changes in miyostatin, irisin, kisspeptin, omentin and leptin levels and the relationship of these changes with physical properties and fat tissue were investigated.Material and Method: A t...

Introduction & Objectives: High consumption of processed foods rich in fat and sugar are associated with the increasing prevalence of metabolic disturbances like obesity, insülin resistance, dyslipidemia, type 2 diabetes mellitus. In the present study, we aimed to investigate the relationship between advanced glycation end products and metabolic disorders such as insulin resistance caused by high fructose and high-fat diet, and also examine histologic...

Aim: The pathophysiology of developing hypophosphatemia in children with diabetic ketoacidosis (DKA) has not been sufficiently elucidated. Fibroblast Growth Factor 23 (FGF23) is a hormone that causes phosphate excretion from the kidneys. The increase of FGF23 in children with DKA may explain the pathophysiology of hypophosphatemia in these children. The aim of our study was to investigate the effect of serum FGF23 on serum phosphorus level in children with DKA...

Introduction and Aim: FGF-23 is a hormone that works by inhibiting phosphorus reabsorption in kidneys, and systematic regulation of phosphate homeostasis by FGF23 depends on the activity of the membrane protein Klotho. It affects the active vitamin level according to the bioactive free vitamin hypothesis, which binds DVBP to vitamin D and prolongs its half-life. In this study, it was aimed to investigate 1.25 (OH) Vitamin D, Vitamin D Binding Protein, FGF-23 a...

Introduction & Objectives: Fat and fructose-rich nutrition bring many metabolic diseases, especially obesity and diabetes. Recent years, more scientific interest in how can diet effect on brain function has emerged. We aimed to investigate the effect of high fructose and high-fat diet on the brain, and whether the presence of relationship with advanced glycation end products histologically, in rat model.Materials & Method...